PharmaGABA features a natural source of the inhibitory neurotransmitter – GABA. GABA supports restful sleep, acts like a "brake" on stress, and provides a focused state of mind.
Gamma-aminobutyric acid (GABA) is a major calming brain chemical or neurotransmitter. Clinical studies show that the natural form of GABA that is in Thorne's PharmaGABA can decrease the brain's stress-related beta waves and increase the production of its alpha-waves, creating a profound sense of physical relaxation while maintaining mental focus. Other studies have shown reduced pupil diameter, heart rate, and two natural biomarkers of stress – salivary cortisol and chromogranin A – all signs of relaxation. In addition, studies also indicate GABA can enhance sleep. In a head-to-head, double-blind trial of natural PharmaGABA versus synthetic GABA, the synthetic GABA did not demonstrate these positive effects. PharmaGABA-250 offers 250 mg of natural GABA per capsule, while PharmaGABA-100 offers 100 mg per capsule. Both are non-habit forming.